Pharmaceutical standardization and physicochemical analysis of Manspachak Vati

Abstract

In the ancient Ayurvedic texts, numerous formulations of herbal, mineral, and herbomineral origin are described. These formulations exhibit therapeutic efficacy in various diseases based on their inherent qualities and properties. The present study focuses on Manspachak Vati, a purely herbal preparation. In Charak Samhita, Uttarsthana, Acharya Charak has described Pachak Yoga for the management of Vishamjwara, and “Manspachak Yoga” is specifically indicated for Mansagat Jwara. Ayurvedic practitioners routinely prescribe Manspachak Yoga in different dosage forms—such as kashaya (decoction) and churna (powder)—as per convenience.

The choice of dosage form plays a crucial role in the drug’s action, absorption, and targeted delivery within the body. Tablets are widely preferred due to their ease of preparation, packaging, transport, and patient-friendly administration. Therefore, in this study, Manspachak Yoga was converted into tablet form using modern manufacturing equipment and analytical techniques.

An attempt was made to validate the pharmaceutical and analytical procedures to ensure consistent product quality and minimize batch-to-batch variation. Pharmacopoeial standards were established for this Ayurvedic formulation in tablet form. All three prepared batches exhibited uniform characteristics, and the analytical parameters showed no significant variation. These established standards may serve as a reference for future pharmaceutical preparations.