According to Ayurved, Twacha is the Updhatu of Mamsa Dhatu. Skin is believed to be formed by the metabolism of Rakhta Dhatu; a phenomenon similar to the formation of cream over milk, when it is made to cool after heating: ‘Ksheerasya Eva Santanika’. Skin (Twacha) is the largest organ of the body and has a great cosmetic value. This article describes Twacha in all respects of KriyaSharir, i.e, Twacha-as an Indriya and its role in sensation of touch, understanding the concept of ‘Dynan Graham Prakriya’. Twacha related Dosha and their functions, Vruddha and KsheenaDosha effects on Twacha, Twacha as Updhatu of Mamsa, Twacha –as one of the MoolaSthana of MamsavahaStrotas, SaptaTwacha and its modern co-relation with skin and Twak Saar PurushLaxanas. At the end, it was also important to mention Twak pariksha as a tool in AshtaVidha Rogi Parikshaa boon of Ayurved to mankind.