A Randomized Controlled Clinical Evaluation of Night-Time Draksha Infusion Water in the Management of Acid-Peptic Symptoms.
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Keywords:
Draksha, Acid Peptic Symptoms, AmlapittaAbstract
ABSTRACT
Acid-peptic disorders correlate with Amla Pitta in Ayurveda, arising from Pitta prakopa along with vishama ahara, raatri jagarana and mental stress. Draksha (Vitis vinifera) is described as Sheetala, Mridu, Pitta-shamaka and Raktaprasadana, beneficial in Amlapitta and hyperacidity. Although Draksha is widely used, its therapeutic effect as night-soaked infusion water has not been clinically evaluated. This study aimed to assess the efficacy of night-time Draksha infusion water, intake in morning for reducing acid-peptic symptoms.
METHODS
A randomized controlled clinical study was conducted on 20 adults (18–50 years) fulfilling inclusion criteria for functional acid-peptic symptoms (non-ulcer dyspepsia) with classical Amlapitta lakshanas. Subjects were randomized into two groups (n=10 each):
- Intervention Group: Night-time Draksha Infusion Water (10–12 raisins) soaked overnight in 100 ml water; infusion consumed on empty stomach in morning.
- Control Group: 100 ml plain water on empty stomach in morning.
RESULTS
The Draksha infusion group showed a significant reduction in epigastric burning, reflux episodes and Amlapitta symptoms compared to the control group. Improvement in Agni and decreased need for antacids were observed. No adverse events occurred.
DISCUSSION
Draksha’s Sheetala, Pittashamaka, Mridu Rechana and Vata-Anulomana properties help pacify aggravated Pitta and soothe the upper GI tract. The infusion format enhances bio-availability and mild Anulomana without heaviness.
CONCLUSION
Night-time Draksha infusion water is a safe, novel and effective Ayurvedic intervention for acid-peptic symptoms, showing promising results for future large-scale RCTs.
KEYWORDS
Draksha, Acid Peptic Symptoms, Amlapitta.
References
1. Charaka Samhita, Chikitsasthana 15 – Amlapitta Chikitsa, Chaukhambha Surbharati Prakashan, Varanasi.
2. Ashtang Hrudaya, Nidanasthana 12 & Chikitsasthana 10, Chaukhambha Orientalia, Varanasi.
3. Bhavaprakasa Nighantu, Phala Varga – Draksa, Chaukhambha Bharati Academy, Varanasi.
4. Vakil N, et al., American Journal of Gastroenterology, 2006;101(8):1900–1920.
→ Standard definition and symptom-based evaluation of acid-peptic/GERD disorders.
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→ Validation of GSRS used as primary outcome measure.
6. Williamson G, et al., British Journal of Nutrition, 2017;118(6):1–13.
→ Supports antioxidant, anti-inflammatory, and mucosal protective effects of grapes/raisins.
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→ Biomedical basis of reflux symptoms, lifestyle and non-pharmacological measures.
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