A critical study to evaluate the importance and prospects of standardization of bhasmas.
Keywords:
Standardization, Bhasma, Physicochemical evaluationAbstract
ABSTRACT
Ayurveda is the oldest surviving complete medical system in the world. Rasashastra and Bhaishajya kalpana is one of the branch of ayurveda that deals with the pharmaceutical processing, preparations of compound medicines and therapeutic utility of metals and minerals. There is always a necessity to properly define the identity of raw material as well as its consistency with respect to specifications. Bhasmas are unique Ayurvedic metallic preparations with herbal juices/fruits widely used for treatment of a variety of chronic ailments. Standardization of bhasma is utmost necessary to confirm its identity and to determine its quality and purity. It will also make sure the safety, effectiveness and acceptability of the product. But the most important challenges faced by these formulations are the lack of complete standardization by physicochemical, microbiological and analytical evaluation. An attempt has been made to summarize various methods available for standardization of bhasma.
Downloads
References
2. Wadekar MP, Patel RK, Preparation and characterization of a copper based Indian traditional drug: Tamra bhasma, Journal of Pharmaceutical and Biomedical Analysis, 39, 2005, 951–955.
3. Tripathi YB, Singh VP, Role of Tamra bhasma, an Ayurvedic preparation, in the management of lipid peroxidation in liver of albino rats, Indian J. Exp. Biol., 34, 1996, 66–70.
4. Sagar Bhanu PS, Zafar R, Panwar R, Herbal drug standardization, The Indian Pharmacist, 4(35), 2005, 19-22.
5. Patel PM, Patel NM, Goyal RK, Quality control of herbal products, The Indian Pharmacist, 5(45), 2006, 26-30.
6. Bhutani KK, Herbal medicines an enigma and challenge to science and directions for new initiatives, Indian Journal of Natural Products, 19 (1), 2003, 3-8.
7. Kokate CK, Purohit AP, Gokhale SB, Analytical pharmacognosy, Pharmacognosy, 30th edition, 2005, pp.1-99.
8. Kapoor RC, Some observations on the metal-based preparations in the Indian Systems of Medi-cine, Indian Journal of Traditional Knowledge, 9 (3), 2010, 562-563.
9. Shrikumar S, Maheshwari U, Sughanti A, Ravi TK, WHO guidelines for herbal drug standardiza-tion, 2006.
10. Shinde, Application of Quality Control Principles to Herbal Drugs, International Journal of Phytomedicine, 1, 2009. 4-8.
11. Shudaldev mohaptra, Physicchemical characterization of ayurvedic bhasma (swarna mashika bhasma):an approach to standardization, International Journal of Ayurveda Research, 1, 2010, 82-83.
12. Bhanu prakash, Use of metals in ayurvedic medicine, Indian journal of history of science, 32(1), 1997, 1-7.
13. Sunil Kumar Singh, Preparation and characterization of a mercury based Indian traditional drug-Ras-Sindoor, Indian Journal of Traditional Knowledge, 8 (3), 2009, 346-347.
14. Tridib Kumar Bhowmick, Physicochemical characterization of an Indian traditional medicine, Jasada Bhasma: detection of nanoparticles containing non-stoichiometric zinc oxide, J Nanopart Res, 2009, 655–664.
15. Prasanta Kumar Sarkar, Ayurvedic Bhasma: the most ancient application of nanomedicine, Journal of Scientific & Industrial research, 69, 2010, 901-905.
16. Arun Sudha, Standardization of Metal-Based Herbal Medicines, American Journal of Infectious Diseases, 5 (3), 2009, 193-199.
17. Shukla SS, Approaches towards standardization and quality assessment of herbals, j. Res. Educ. Indian Med., 15(1), 2009, 25-32.
18. Arvind kumar Sharma, A rapid and simple scheme for standardization of poly herbal drugs, Indian journal of green pharmacy, 2010, 134-135.
19. Singh, Synthesis, Characterization and Histopathological Study of a Lead-Based Indian Tradi-tional Drug: Naga Bhasma, Indian journal of pharmaceutical Science, 2010, 24.
20. Bhowmick, Tridib Kumar, Suresh, Akkihebbal K, Kane, Shantaram G, Joshi, Ajit C, Bellare, Jayesh R, Physicochemical characterization of an Indian traditional medicine, Jasada Bhasma: detection of nanoparticles containing non-stoichiometric zinc oxide, Journal of Nanoparticle Research, 11 (3), 2009, 655-664.
21. Wadekar MP, Rodeb CV, Bendale YN, Patil KR, Prabhune AA, Preparation and characterization of a copper based Indian traditional drug: Tamra bhasma, Journal of Pharmaceutical and Bio-medical Analysis, 39, 2005, 951–955.
Downloads
Published
How to Cite
Issue
Section
License
I declare (on behalf of me and my co-authors) that the submitted manuscript titled has not previously been published and is not currently being considered elsewhere for publication in another journal and that I am (we are) the sole owner(s) of the manuscript thereof and of all rights, title, and interest therein. All agreed to the terms and conditions, Privacy Policy, which is declared on Journal Website http://www.ayurline.in and online filled (uploaded) form.
Please read following declaration cum Agreement Carefully.:
I declare (on behalf of me and my co-authors) that the submitted manuscript titled has not previously been published and is not currently being considered elsewhere for publication in another journal and that I am (we are) the sole owner(s) of the manuscript thereof and of all rights, title, and interest therein.
I (We) agree (on behalf of me and my co-authors) to the following:
1- I (we) hereby assign to the publisher of the journal. Ayurline: International Journal of Research in Indian Medicine (IJ-RIM) the right to (Electronically and print) publish on website www.ayurline.in and distribute the said manuscript and to create a derivative print work from the said manuscript. The assignment shall be effective so long as the manuscript is available on online networks.
2- I (we) shall remain the owner of the copyright in said manuscript. I (we) may publish the manuscript in any other journal or medium but such publication must include the notice that the manuscript was first published by Ayurline: International Journal of Research in Indian Medicine (IJ-RIM) Journals including reference to the corresponding issue.
3- I (we) agree to hold the publisher of the Journal, Ayurline: International Journal of Research in Indian Medicine (IJ-RIM) harmless for any unauthorized use of the paper by the journal subscribers.
4- I (we) confirm that I (we) have obtained all the necessary all permissions to include in the paper items such as quotations, figures, and the results of government-sponsored research/private or individual publishers/owners.
5- I (we) enclose where necessary written permission of authors and publishers to use any copyright material (previously published figures and tables).
6- I (we) confirm that after the publication of my (our) manuscript in Ayurline: International Journal of Research in Indian Medicine (IJ-RIM), the publisher has the sole authority of the paper/Research Article. The publisher has the authority to use the content of the whole paper or part of it, in an edited book, or other mediums or withdraw (unpublish) the article without the permission of authors.
8- If I / We found victims of plagiarism, (साहित्यिक चोरी) (e.g. text, images, videos etc.) I/ We sole responsible for such legal matters. I/We also declared that the Chief Editor/Publisher, Editorial Board of this Ayurline: International Journal of Research in Indian Medicine (IJ-RIM) Journal does not have any responsibility for plagiarism. Publisher shall not become any party in any legal matter and if any case is filed in court against plagiarisms or any copyright-related issues all expenses/Penalties should be paid/borne by me/we (Authors). I shall be obliged to pay all the costs of the court case if any happened in future.
7 -I voluntarily agreed to pay the necessary non-refundable evaluation fees of the my article, which are not the publication Charges.
8 - All disputes subject to Kurla, Mumbai court jurisdiction. This Copyright Licensing Agreement comes into force the day of sending this completed electronic form.